What is Sensitization?

Sensitization in the context of addiction refers to a process by which repeated exposure to drugs or other addictive substances can lead to increased sensitivity or responsiveness to their effects. This can result in an increased likelihood of substance use, stronger drug-seeking behavior, and a heightened psychological response to the substance. 

Sensitization is thought to be a key factor in the development and maintenance of addiction, as repeated drug use can alter brain structure and function, leading to changes in the reward system, motivation, and decision-making. The process of sensitization can also increase the likelihood of relapse, as it can cause individuals to respond strongly to even small amounts of the substance or cues related to drug use, making it difficult to resist the urge to use. Understanding the role of sensitization in addiction is important for developing effective treatments and interventions to support individuals in their recovery journey.

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