Dictionary

Downers is a slang term used to describe central nervous system (CNS) depressants, a class of psychoactive substances that slow down brain function and decrease activity in the central nervous system. CNS depressants work by enhancing the activity of the neurotransmitter gamma-aminobutyric acid (GABA), which slows down brain activity. Some commonly known downers include alcohol, barbiturates, benzodiazepines, and opiates. These drugs are used medically to treat various conditions, such as anxiety, insomnia, and seizures, but they can also be abused for their sedative and relaxing effects.

Regular use of downers can lead to tolerance, dependence, and withdrawal symptoms. Overdose from CNS depressants can be life-threatening, and abuse of these substances can lead to serious health problems, including respiratory depression and cardiac arrest. Downers are often used recreationally to produce feelings of relaxation, calmness, and sedation. However, they can also produce adverse side effects such as impaired cognitive and motor function, decreased inhibitions, and memory problems. In general, downers should only be used under the supervision of a medical professional and should never be used in combination with other CNS depressants or alcohol.