High affinity drugs are drugs that have a strong binding and attraction to their target site, such as a receptor. They have a high ability to bind and activate the receptor, resulting in a potent therapeutic effect.
High affinity drugs bind specifically and tightly to their target site, reducing the likelihood of binding to other sites that may not be the intended target. This results in increased efficacy and reduced side effects. High affinity drugs may also require lower doses to achieve the desired therapeutic effect compared to low affinity drugs.